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KMID : 0617919840020010195
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Wonkwang Oriental Medicine
1984 Volume.2 No. 1 p.195 ~ p.206
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The Effect of Hwang Hae Dok Tang on the Immune Response to Sheep Red Blood Cells
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송대준
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Abstract
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In the herb medicine, it has long been said that Hwang Ryon Hae Dok Tang (HRHDT) is effective in alleviating fever, antidoting, resistance to infection, treatment of tumor.
This experiment was undertaken to evaluate the effect of HRHDT on the mice were sensitized intraperitoneally with SRBC(sheep red blood cells) and were challenged 4days later. In this study, the auther observed the effects of HRHDT on the cellular and humoral inmune response. The celluar immune response was determined by measuring the footpad swelling reaction. Footpad swelling reaction of each mouse was measured at 3hrs(Arthus reaction) and 24hrs(delayed type hypersensitivity) after challenge. The humoral immune response was determined by measuring hemagglutinins to SRBC.
Following results have been obtained.
1. Arthus reaction and delayed type hypersensitivity of mice HRHDT administe red were decreased than those of control mice.
2. The serum antibody titers of mice HRHDT administered were decreased than those of control mice.
3. There has not been noticeable differences among the groups during the pre-immunization, pro-immunization and through the period.
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KEYWORD
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